Description

[1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Chloro- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients, especially those with purine or pyrimidine-like structures.
• Biochemical Research: Used as a reference standard or a substrate in enzymatic and receptor-binding studies within life science research.
• Process Chemistry Development: Employed by process chemists to develop and optimize scalable, cost-effective synthetic routes for complex molecules.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations producing custom intermediates for client-specific drug development pipelines.

Basic Information

Product Name	[1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Chloro-
CAS No.	191936-48-8
Molecular Formula	C19H18ClN5O3
Molecular Weight	399.83 g/mol
Synonyms	4-Chloro-N-[4-amino-1-methyl-2,6-dioxo-1,2,3,6-tetrahydro-5-pyrimidinyl][1,1'-biphenyl]-4-acetamide; 4'-Chloro-4-biphenylacetic acid 4-amino-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-5-ylamide; 5-[[(4'-Chloro[1,1'-biphenyl]-4-yl)acetyl]amino]-1-methyl-1,2,3,6-tetrahydro-2,6-pyrimidinedione; 191936-48-8; Biphenyl-4-acetamide, N-(4-amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)-4'-chloro-
EINECS	Contact for details

Quality Control

Our [1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.