Description

3-Bromo-4-(Trifluoromethoxy)Aniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethoxy substituents, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for electron-transport materials, host materials, and other functional components in display and lighting technologies.
• Polymer Modification: Incorporated into polymer backbones to impart specific properties such as flame retardancy, chemical resistance, and altered refractive indices.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast organic dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	3-Bromo-4-(Trifluoromethoxy)Aniline
CAS No.	191602-54-7
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	3-Bromo-4-(trifluoromethoxy)benzenamine; 3-Bromo-4-trifluoromethoxyaniline; 4-Amino-2-bromo-1-(trifluoromethoxy)benzene; 2-Bromo-4-amino-1-(trifluoromethoxy)benzene; Benzenamine, 3-bromo-4-(trifluoromethoxy)-; 191602-54-7; 3-Bromo-4-(trifluoromethoxy)phenylamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Trifluoromethoxy)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency meet the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.