Description

Fmoc-Tyr(Po(Obzl)OH)-OH is a protected tyrosine derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound matters as a critical building block for the controlled introduction of phosphorylated tyrosine residues, enabling the study of protein phosphorylation and signaling pathways. It is essential for researchers and manufacturers in pharmaceutical R&D, biotechnology, and academic research focused on peptide-based therapeutics and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of phosphopeptides.
• Phosphopeptide Production: For creating research-grade and therapeutic peptides that mimic phosphorylated proteins.
• Biochemical Research: Used in studies of kinase and phosphatase activity, signal transduction mechanisms, and protein-protein interactions.
• Drug Discovery: Serves as an intermediate in the development of peptide-based inhibitors targeting phosphorylated protein domains.
• Diagnostic Reagent Development: For producing antigens and standards in immunoassays detecting phospho-specific antibodies.
• Chemical Biology Probes: Incorporation into activity-based probes to study phosphorylation events in live cells.

Basic Information

Product Name	Fmoc-Tyr(Po(Obzl)OH)-OH
CAS No.	191348-16-0
Molecular Formula	C32H30NO8P
Molecular Weight	587.56 g/mol
Synonyms	Fmoc-O-benzylphosphotyrosine; Fmoc-Tyr(PO(OBzl)OH)-OH; N-(9-Fluorenylmethoxycarbonyl)-O-(dibenzylphosphono)tyrosine; Fmoc-phosphotyrosine(O-benzyl); Fmoc-P-Tyr(OBzl)-OH; Fmoc-Tyr(PO3Bzl2)-OH; (2S)-3-(4-{[bis(benzyloxy)phosphoryl]oxy}phenyl)-2-[(9H-fluoren-9-ylmethoxy)formamido]propanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Tyr(Po(Obzl)OH)-OH is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.