Description

3-(2-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated aromatic ester building block. This compound is prized for its role in introducing the trifluoromethylphenyl moiety, a key structural feature that can enhance the metabolic stability, lipophilicity, and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modifier: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or optical properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new reactions involving fluorinated aromatics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke fine chemicals and complex molecules for client projects.

Basic Information

Product Name	3-(2-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	191155-80-3
Molecular Formula	C₁₂H₁₃F₃O₂
Molecular Weight	246.23 g/mol
Synonyms	Ethyl 3-[2-(Trifluoromethyl)phenyl]propanoate; 3-[2-(Trifluoromethyl)phenyl]propionic Acid Ethyl Ester; 2-(Trifluoromethyl)benzenepropanoic Acid Ethyl Ester; Ethyl 3-(2-Trifluoromethylphenyl)propionate; α,α,α-Trifluoro-o-toluic Acid Ethyl Ester (related); o-Trifluoromethylphenylpropionic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is produced and tested under a strict quality management system. We guarantee high chemical purity and consistency, with comprehensive testing including identity confirmation, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.