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n-W,W-Dimethy-D-Arginine(Symmetrical) CAS NO 190784-53-3
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CAS No.:190784-53-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-W,W-Dimethy-D-Arginine(Symmetrical) is a high-purity, non-natural amino acid derivative of D-Arginine. This compound is valued for its role as a critical building block and chiral auxiliary in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and conducting structure-activity relationship studies.
Application
- Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving nitric oxide synthase (NOS) and arginase pathways.
- Peptide Chemistry: Incorporated into custom peptides to study structure-function relationships, stability, and receptor binding affinity.
- Asymmetric Synthesis: Acts as a chiral auxiliary or catalyst ligand in stereoselective organic transformations.
- Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
Basic Information
| Product Name | n-W,W-Dimethy-D-Arginine(Symmetrical) |
| CAS No. | 190784-53-3 |
| Molecular Formula | C8H18N4O2 |
| Molecular Weight | 202.25 g/mol |
| Synonyms | Nω,Nω-Dimethyl-D-arginine; D-NG,NG-Dimethylarginine; Symmetrical Dimethyl-D-arginine; D-SDMA; (R)-2-Amino-5-[(dimethylamino)imino]pentanoic acid; H-D-Arg(Me)2-OH; ADMA (D-isomer) |
| EINECS | Contact for details |
Quality Control
Our n-W,W-Dimethy-D-Arginine(Symmetrical) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Purity (Chiral HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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