Description

n-α-(9-Fluorenylmethyloxycarbonyl)-n-T-Butyloxycarbonyl-L-Canavanine is a protected derivative of the non-proteinogenic amino acid L-canavanine, specifically designed for solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise, high-purity building blocks for advanced peptide and protein chemistry. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the synthesis of complex peptides and peptidomimetics where the controlled incorporation of the canavanine moiety is essential.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key, orthogonally protected building block for the controlled introduction of L-canavanine into peptide chains.
• Pharmaceutical Research & Development: Used in the synthesis of novel therapeutic peptides, enzyme inhibitors, and bioactive compounds targeting specific biological pathways.
• Bioconjugation and Chemical Biology: Enables the site-specific modification of peptides and proteins for probe development, drug delivery systems, and diagnostic applications.
• Academic and Industrial Research: A fundamental reagent for studying arginine analogs, nitric oxide synthase inhibition, and structure-activity relationships in peptide science.
• Production of Reference Standards: Employed in the synthesis of high-purity peptide standards for analytical method development and quality control.

Basic Information

Product Name	n-α-(9-Fluorenylmethyloxycarbonyl)-n-T-Butyloxycarbonyl-L-Canavanine
CAS No.	190723-97-8
Molecular Formula	C26H31N3O7
Molecular Weight	497.54 g/mol
Synonyms	Fmoc-Nω-Boc-L-Canavanine; Nα-Fmoc-Nω-Boc-L-canavanine; Fmoc-L-Canavanine(Nω-Boc)-OH; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino-5-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid; L-Canavanine, Nα-Fmoc, Nω-Boc-; Fmoc-Canavanine(Boc)-OH; Boc-L-Canavanine(Fmoc)-OH
EINECS	Contact for details

Quality Control

Our n-α-(9-Fluorenylmethyloxycarbonyl)-n-T-Butyloxycarbonyl-L-Canavanine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.