Description

4-Dimethylcarbamoyl-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its primary value lies in its role as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require a high-purity, reliable reagent for sulfonamide and sulfonate formation.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonyl moiety is a key pharmacophore.
• Chemical Research & Development: Serves as a versatile electrophile in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized sulfonated dyes and colorants.
• Polymer Chemistry: Can be used to introduce sulfonyl chloride functional groups into polymers for further modification.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring the introduction of a dimethylcarbamoyl-benzenesulfonyl group.

Basic Information

Product Name	4-Dimethylcarbamoyl-Benzenesulfonyl Chloride
CAS No.	190711-50-3
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	4-(Dimethylcarbamoyl)benzenesulfonyl chloride; N,N-Dimethyl-4-sulfamoylbenzamide chloride; p-(Dimethylcarbamoyl)benzenesulfonyl chloride; 4-Carbamoylbenzenesulfonyl chloride, N,N-dimethyl-; Benzenesulfonyl chloride, 4-(dimethylaminocarbonyl)-; 190711-50-3; (4-(Dimethylcarbamoyl)phenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Dimethylcarbamoyl-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0 - 103.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.