Description

2-Amino-5,6-Difluoroquinazoline is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its value lies in its unique difluoro-substituted quinazoline core, which is a privileged scaffold for modulating the biological activity and physicochemical properties of target molecules. This advanced intermediate is essential for medicinal chemistry research and development, particularly for organizations engaged in the synthesis of novel pharmaceutical compounds and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for the synthesis of organic electronic materials and fluorescent dyes.
• Chemical Biology: Employed as a probe or linker in the design of biochemical tools and diagnostic agents.
• Academic & Contract Research: Critical for exploratory synthetic chemistry and structure-activity relationship (SAR) studies in academic and CRO settings.

Basic Information

Product Name	2-Amino-5,6-Difluoroquinazoline
CAS No.	190273-85-9
Molecular Formula	C8H5F2N3
Molecular Weight	181.15 g/mol
Synonyms	5,6-Difluoro-2-quinazolinamine; 5,6-Difluoroquinazolin-2-amine; 2-Amino-5,6-difluoroquinazoline; 190273-85-9; Quinazoline, 2-amino-5,6-difluoro-; 2-Quinazolinamine, 5,6-difluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-5,6-Difluoroquinazoline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.