Description

3-Chloro-2,6-Difluorobenzaldehyde is a versatile aromatic aldehyde building block distinguished by its strategically placed halogen substituents. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core with an aldehyde handle for further derivatization.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the chloro and fluoro groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	3-Chloro-2,6-Difluorobenzaldehyde
CAS No.	190011-87-1
Molecular Formula	C7H3ClF2O
Molecular Weight	176.55 g/mol
Synonyms	2,6-Difluoro-3-chlorobenzaldehyde; 3-Chloro-2,6-difluorobenzenecarboxaldehyde; Benzaldehyde, 3-chloro-2,6-difluoro-; 190011-87-1; 3-Chloro-2,6-difluoro-benzaldehyde; 3-Chloro-2,6-difluorobenzaldehyde (CAS 190011-87-1)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,6-Difluorobenzaldehyde is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light. Due to its aldehyde functionality and potential for oxidation, it is recommended to handle under an inert atmosphere for long-term storage of opened containers. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.