Description

Fmoc-D-3,3-Diphenylalanine is a high-purity, non-natural amino acid derivative extensively used in solid-phase peptide synthesis (SPPS). This compound is critical for introducing the unique, bulky D-3,3-diphenylalanine residue into peptide sequences, which can significantly alter the peptide's conformation, stability, and biological activity. It is an essential building block for researchers and manufacturers in pharmaceutical R&D, particularly for developing novel therapeutic peptides, peptidomimetics, and as a tool in chemical biology studies.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel therapeutic peptides and peptidomimetics targeting various diseases.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected amino acid building block for the controlled assembly of complex peptide chains.
• Chemical Biology & Proteomics: Used to create peptide probes, inhibitors, and labeled compounds for studying protein-protein interactions and enzyme function.
• Structure-Activity Relationship (SAR) Studies: Incorporation of the D-3,3-diphenylalanine side chain helps elucidate the impact of steric bulk and chirality on peptide bioactivity.
• Material Science & Specialty Polymers: Potential monomer for creating novel bio-inspired polymers and advanced materials with specific properties.

Basic Information

Product Name	Fmoc-D-3,3-Diphenylalanine
CAS No.	189937-46-0
Molecular Formula	C31H27NO4
Molecular Weight	477.55 g/mol
Synonyms	Fmoc-D-3,3-diphenyl-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3,3-diphenyl-D-alanine; Fmoc-D-Diphenylalanine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid; Fmoc-D-3,3-Ph2Ala-OH; N-Fmoc-3,3-diphenyl-D-alanine; BOC Sciences Brand Name: BBL-BB-013003
EINECS	Contact for details

Quality Control

Our Fmoc-D-3,3-Diphenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), and impurity profiles is provided with every shipment to guarantee reproducible results in your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.