Description

Ro 10-5824 is a high-purity, small molecule compound with the CAS number 189744-94-3, primarily utilized as a potent and selective dopamine D4 receptor partial agonist in advanced research. This specificity makes it a critical tool for investigating neurological pathways and developing novel therapeutic agents targeting psychiatric and cognitive disorders. It is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies focused on neuroscience, neuropharmacology, and central nervous system (CNS) drug discovery.

Application

• Neuroscience Research: A key pharmacological tool for studying the function and distribution of dopamine D4 receptors in the brain.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel antipsychotic and cognitive-enhancing medications.
• Pharmacological Profiling: Employed in in vitro and in vivo assays to evaluate receptor binding affinity, selectivity, and functional activity.
• Academic & Institutional Research: Supports fundamental research into dopamine signaling pathways, behavioral models, and neurological disease mechanisms.
• Biomarker Studies: Aids in research exploring the role of the D4 receptor in conditions such as schizophrenia, attention deficit hyperactivity disorder (ADHD), and addiction.

Basic Information

Product Name	Ro 10-5824
CAS No.	189744-94-3
Molecular Formula	C₁₉H₂₅N₅O₂
Molecular Weight	355.44 g/mol
Synonyms	Ro-10-5824; Ro105824; 4-(2-Pyrazinyl)piperazinyl]benzimidazole derivative; Dopamine D4 receptor partial agonist; N-[(2S)-1-(5-Chloro-2-pyrimidinyl)-2-pyrrolidinyl]methyl]-1H-benzimidazol-2-amine
EINECS	Contact for details

Quality Control

Our Ro 10-5824 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.