Description

2-Acetamido-2-Deoxy-A-D-Galactopyranosyl-(n-Fmoc)-L-Threonine tert-Butyl Ester is a sophisticated, protected carbohydrate-amino acid conjugate designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring high-purity, structurally defined building blocks for complex biomolecule assembly. It is primarily utilized in the pharmaceutical and biotechnology sectors for the synthesis of glycopeptides, glycoproteins, and other biologically active molecules where precise glycosylation is essential.

Application

• Glycopeptide Synthesis: Serves as a key protected intermediate for the solid-phase and solution-phase synthesis of complex glycopeptides, enabling the study of glycosylation effects on protein function and stability.
• Pharmaceutical Research: Used in the development of novel therapeutic agents, including vaccines, antibiotics, and targeted cancer therapies that exploit carbohydrate-protein interactions.
• Bioconjugation: Acts as a specialized building block for creating defined glycan structures on surfaces, nanoparticles, or other biomolecules for diagnostic and drug delivery applications.
• Enzyme Substrate & Inhibitor Development: Employed in biochemical research to study glycosyltransferases, glycosidases, and other carbohydrate-processing enzymes.
• Chemical Biology Probes: Facilitates the creation of labeled or tagged glycoconjugates for imaging, pull-down assays, and pathway analysis within living systems.

Basic Information

Item	Details
Product Name	2-Acetamido-2-Deoxy-A-D-Galactopyranosyl-(n-Fmoc)-L-Threonine tert-Butyl Ester
CAS No.	189561-75-9
Molecular Formula	C32H40N2O11
Molecular Weight	628.67 g/mol
Synonyms	Fmoc-Thr(tBu)-GalNAc; N-α-Fmoc-O-(2-acetamido-2-deoxy-α-D-galactopyranosyl)-L-threonine tert-butyl ester; Fmoc-L-Threonine(3-O-(2-acetamido-2-deoxy-α-D-galactopyranosyl)) tert-butyl ester; GalNAc-α-Thr(tBu)-Fmoc; O-(2-Acetamido-2-deoxy-α-D-galactopyranosyl)-N-α-(9-fluorenylmethoxycarbonyl)-L-threonine tert-butyl ester; Protected Tn antigen building block; α-GalNAc-Thr(Fmoc)-OtBu
EINECS	Contact for details

Quality Control

Every batch of 2-Acetamido-2-Deoxy-A-D-Galactopyranosyl-(n-Fmoc)-L-Threonine tert-Butyl Ester is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and cGMP-grade pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.