Description

Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (-)- (9Ci) CAS NO 189445-63-4 is a chiral, fluorinated aromatic aldehyde derivative, serving as a sophisticated and versatile building block in advanced organic synthesis. Its core value lies in the precise introduction of both fluorine and a chiral center into molecular scaffolds, enabling the fine-tuning of physicochemical and biological properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated active pharmaceutical ingredients (APIs), including potential CNS agents and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in creating advanced, fluorinated pesticides and herbicides where the chiral center and fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals where fluorination and chirality impart unique material properties.
• Flavor and Fragrance Chemistry: Acts as a potential intermediate for complex, high-value aromatic compounds.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in fluorination and stereoselective reactions.

Basic Information

Product Name	Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (-)- (9Ci)
CAS No.	189445-63-4
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	(-)-4-Fluoro-α-methylbenzeneacetaldehyde; (S)-4-Fluoro-α-methylphenylacetaldehyde; 4-Fluoro-α-methylbenzeneacetaldehyde, (-)-; 4-Fluoro-α-methylphenylacetaldehyde; (S)-2-(4-Fluorophenyl)propanal; 1-(4-Fluorophenyl)propanal, (S)-; Benzeneacetaldehyde, 4-fluoro-α-methyl-, (αS)-; (S)-4-Fluoro-α-methylbenzenecetaldehyde
EINECS	Contact for details

Quality Control

Our Benzeneacetaldehyde, 4-Fluoro-α-Methyl-, (-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC/GC, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.