Description

Benzeneacetaldehyde, 2-Fluoro-α-Methyl-, (-)- (9Ci) is a chiral, fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its core value proposition lies in the precise introduction of both fluorine and a chiral center into molecular scaffolds, enabling the fine-tuning of physical, chemical, and biological properties. This high-purity intermediate is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials. The compound, identified by CAS number 189445-62-3, is supplied to meet the stringent demands of process chemistry and discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the construction of advanced, fluorinated herbicides, fungicides, and insecticides where the chiral center can influence biological activity and environmental fate.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals where fluorine incorporation modifies thermal stability and optical properties.
• Flavor and Fragrance Chemistry: Acts as a high-value intermediate for creating complex, fluorinated aroma chemicals with unique sensory profiles.
• Academic and R&D Laboratories: A valuable tool for methodological studies in fluorination chemistry and asymmetric synthesis.

Basic Information

Item	Detail
Product Name	Benzeneacetaldehyde, 2-Fluoro-α-Methyl-, (-)- (9Ci)
CAS No.	189445-62-3
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	(-)-2-Fluoro-α-methylbenzeneacetaldehyde; (S)-2-Fluoro-α-methylphenylacetaldehyde; 2-Fluoro-α-methylbenzeneacetaldehyde; (2-Fluorophenyl)acetaldehyde, α-methyl-, (S)-; α-Methyl-2-fluorobenzeneacetaldehyde; (S)-2-(2-Fluorophenyl)propanal; 2-Fluoro-α-methylphenylacetic aldehyde
EINECS	Contact for details

Quality Control

Our Benzeneacetaldehyde, 2-Fluoro-α-Methyl-, (-)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by GC/HPLC), chiral purity (by chiral HPLC), and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to support regulatory filings for our customers in advanced markets.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its properties of being easily oxidized and highly volatile, the container must be kept sealed and allowed to reach ambient temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.