Description

Endomorphin-1 is a potent, highly selective endogenous opioid peptide that acts as a mu-opioid receptor agonist. This compound is of significant interest in advanced neuroscience and pharmaceutical research due to its role in modulating pain perception and its potential therapeutic applications. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuropharmacology, analgesic development, and receptor studies.

Application

• Neuroscience Research: Used as a critical tool for studying the function and signaling pathways of the mu-opioid receptor (MOR) in the central nervous system.
• Analgesic Drug Discovery: Serves as a reference standard and lead compound in the development of novel, non-addictive pain management therapies.
• Biochemical Assays: Employed in competitive binding assays, receptor autoradiography, and functional studies to evaluate ligand-receptor interactions.
• Pharmacology Studies: Investigated for its physiological roles in stress response, emotional regulation, and reward mechanisms.
• Peptide Chemistry Reference: Used as a high-purity standard for analytical method development and validation in peptide analysis.

Basic Information

Product Name	Endomorphin-1
CAS No.	189388-22-5
Molecular Formula	C34H50N8O7
Molecular Weight	682.82 g/mol
Synonyms	Tyr-Pro-Trp-Phe-NH2; Endomorphin 1; H-Tyr-Pro-Trp-Phe-NH2; Endomorphism-1; EM-1; Mu-opioid receptor agonist peptide; Opioid peptide Tyr-Pro-Trp-Phe-NH2
EINECS	Contact for details

Quality Control

Our Endomorphin-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed chromatographic data, ensuring traceability and compliance with research-grade standards. Stability studies are conducted to guarantee performance throughout the product's shelf life.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.