Description

Clorazepate is a benzodiazepine derivative, recognized as a key pharmaceutical intermediate and active pharmaceutical ingredient (API). Its primary value lies in its anxiolytic and sedative properties, making it essential for the development of controlled therapeutic formulations. This compound is critical for pharmaceutical manufacturers and research institutions focused on central nervous system (CNS) drug development and generic API production.

Application

• Pharmaceutical API Synthesis: Primary use as the active ingredient in the manufacture of anxiolytic and sedative medications.
• Generic Drug Production: Serves as a critical building block for formulating generic versions of benzodiazepine-based drugs.
• Neuropharmacology Research: Used in preclinical and clinical research to study GABA receptor modulation and CNS effects.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for drug testing and verification.
• Formulation Development: Integral to R&D for developing new dosage forms, including tablets and controlled-release systems.

Basic Information

Product Name	Clorazepate
CAS No.	189298-40-6
Molecular Formula	C16H11ClN2O3
Molecular Weight	314.72 g/mol
Synonyms	Clorazepic Acid; Clorazepate Dipotassium (salt form); 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid; Azene; Tranxene; 4306 CB; Abbott 35616; Dipotassium Clorazepate; Clorazepate Monopotassium
EINECS	Contact for details

Quality Control

Our Clorazepate is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested for identity, purity, and impurities using validated analytical methods, including HPLC and IR spectroscopy. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specification results. We adhere to cGMP principles, and our quality systems are designed to support regulatory filings for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.