Description

Clorazepate is a benzodiazepine derivative, recognized for its pharmacological activity as a central nervous system depressant. This compound is a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) for anxiolytic and sedative medications. It is essential for pharmaceutical R&D laboratories and manufacturers engaged in the production of controlled therapeutic agents. Clorazepate CAS NO 189298-39-3 is supplied to meet the stringent purity requirements of the global pharmaceutical supply chain.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of anxiolytic and sedative drug substances.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a direct precursor in the production of finished dosage forms.
• Research & Development: Utilized in pharmacological studies and the development of new central nervous system (CNS) targeting therapies.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control and method validation.
• Chemical Synthesis: Used in organic synthesis for creating novel benzodiazepine analogs and related compounds.

Basic Information

Product Name	Clorazepate
CAS No.	189298-39-3
Molecular Formula	C16H11ClN2O3
Molecular Weight	314.72 g/mol
Synonyms	Clorazepic Acid; 7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic Acid; Dipotassium Clorazepate (salt form); Tranxene (brand name); Azene; Clorazepate Dipotassium; 4306CB; CLZ
EINECS	Contact for details

Quality Control

Our Clorazepate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting purity (typically ≥98% by HPLC), related substances, and residual solvents are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.