Description

Cyclohexanecarboxylic Acid, 2-Amino-, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant importance in advanced organic synthesis. Its rigid cyclohexane backbone and strategically positioned amino and carboxylic acid functional groups make it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise stereochemistry is critical for function.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Peptidomimetics and Bioactive Molecule Synthesis: The constrained cyclohexane ring is utilized to create conformationally restricted peptide analogs and other bioactive compounds.
• Material Science: Potential monomer for the synthesis of specialized polymers with unique thermal or mechanical properties.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Amino-, (1S,2R)- (9Ci)
CAS No.	189101-41-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1S,2R)-2-Aminocyclohexanecarboxylic acid; (1S,2R)-2-Amino-1-cyclohexanecarboxylic acid; cis-2-Aminocyclohexanecarboxylic acid (specific stereoisomer); L-cis-2-Aminocyclohexanecarboxylic acid; ACC (in specific contexts); Chiral C2-substituted cyclohexane derivative; (1S,2R)-ACHC
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanecarboxylic Acid, 2-Amino-, (1S,2R)- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available for each lot. Our quality protocols are designed to support compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.