Description

Nesiritide Citrate is a synthetic form of human B-type natriuretic peptide (hBNP) complexed with citric acid, identified by CAS NO 189032-40-4. This compound is of critical importance in pharmaceutical research and development, particularly for its role in cardiovascular therapeutics. It is primarily required by pharmaceutical manufacturers, biotechnology research firms, and advanced academic laboratories engaged in the development of treatments for acute decompensated heart failure.

Application

• Active Pharmaceutical Ingredient (API) for the formulation of parenteral drugs targeting heart failure.
• Biochemical Research as a standard or reference material in studies of natriuretic peptide systems and cardiovascular physiology.
• Preclinical and Clinical Development of novel therapeutic agents for cardiac conditions.
• Quality Control Laboratories for use as an analytical reference standard in HPLC and other assay methods.
• Process Development for the scale-up and optimization of peptide-based drug manufacturing.

Basic Information

Product Name	Nesiritide Citrate
CAS No.	189032-40-4
Molecular Formula	C143H244N50O46S4 • xC6H8O7
Molecular Weight	3464 g/mol (for peptide base)
Synonyms	Human B-type Natriuretic Peptide (hBNP) Citrate; Natrecor® (Brand Name); BNP (1-32), human; Recombinant Human BNP; hBNP Citrate; Citrate salt of Nesiritide; 189032-40-4
EINECS	Contact for details

Quality Control

Our Nesiritide Citrate is manufactured under strict quality systems suitable for pharmaceutical research. Each batch undergoes rigorous analytical testing to ensure identity, purity, and potency. Certificates of Analysis (COA) detailing comprehensive test results, including assay by HPLC and related substance profiles, are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its hygroscopic nature, the product should be stored in a dry environment. For long-term storage, consider desiccated conditions at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 10.0%
Peptide Content (UV)	≥ 80.0%
Biological Activity	Contact for details
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.