Description

5-(2,3-Dichlorophenyl)-6-(Fluoromethyl)Pyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule drugs.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially in kinase inhibitor programs.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or pesticides with specific activity profiles.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Employed in academic laboratories and corporate R&D centers for exploratory chemistry and process development.

Basic Information

Product Name	5-(2,3-Dichlorophenyl)-6-(Fluoromethyl)Pyrimidine-2,4-Diamine
CAS No.	189013-61-4
Molecular Formula	C11H9Cl2FN4
Molecular Weight	287.12 g/mol
Synonyms	2,4-Diamino-5-(2,3-dichlorophenyl)-6-(fluoromethyl)pyrimidine; 6-(Fluoromethyl)-5-(2,3-dichlorophenyl)pyrimidine-2,4-diamine; 5-(2,3-Dichlorophenyl)-6-fluoromethyl-2,4-pyrimidinediamine; 189013-61-4; 5-(2,3-Dichlorophenyl)-6-(fluoromethyl)-2,4-pyrimidinediamine; Pyrimidine-2,4-diamine, 5-(2,3-dichlorophenyl)-6-(fluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-(2,3-Dichlorophenyl)-6-(Fluoromethyl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.