Description

6-Fluoro-2-[(Phenylmethyl)Amino]-4(1H)-Pyrimidinone is a fluorinated pyrimidinone derivative, a high-value building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a benzylamino group, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production in pharmaceutical chemistry, particularly for creating targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine moiety for enhanced bioactivity and stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential use as a monomer or additive in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	6-Fluoro-2-[(Phenylmethyl)Amino]-4(1H)-Pyrimidinone
CAS No.	189003-13-2
Molecular Formula	C11H10FN3O
Molecular Weight	219.22 g/mol
Synonyms	6-Fluoro-2-(benzylamino)-1,4-dihydropyrimidin-4-one; 6-Fluoro-2-(benzylamino)pyrimidin-4(1H)-one; 2-(Benzylamino)-6-fluoro-4(1H)-pyrimidinone; 6-Fluoro-2-(benzylamino)-4-hydroxypyrimidine; 189003-13-2; 6-Fluoro-2-(phenylmethylamino)-4(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-[(Phenylmethyl)Amino]-4(1H)-Pyrimidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.