Description

2,4-Bis(Piperidino)-6-Fluoropyrimidine is a specialized fluorinated pyrimidine derivative that serves as a valuable building block in advanced organic synthesis. Its molecular structure, featuring both piperidine and fluorine substituents, makes it a key intermediate for creating complex molecules with targeted biological and material properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluoropyrimidine core can contribute to enhanced biological activity and stability.
• Material Science: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorine-containing heterocycles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2,4-Bis(Piperidino)-6-Fluoropyrimidine
CAS No.	188987-72-6
Molecular Formula	C14H21FN4
Molecular Weight	264.35 g/mol
Synonyms	6-Fluoro-2,4-dipiperidin-1-ylpyrimidine; 2,4-Dipiperidino-6-fluoropyrimidine; 6-Fluoro-2,4-bis(piperidin-1-yl)pyrimidine; 1,1'-(6-Fluoropyrimidine-2,4-diyl)dipiperidine; 2,4-Bis(1-piperidinyl)-6-fluoropyrimidine; 188987-72-6; 6-Fluoro-2,4-di(piperidin-1-yl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Piperidino)-6-Fluoropyrimidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.