Description

Ethyl 4-Chloro-2-Thien-2-Ylpyrimidine-5-Carboxylate is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is crucial for the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel pesticides and herbicides.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemicals.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and novel reaction methodology development.
• Chemical Library Production: A valuable scaffold for creating diverse compound libraries for biological screening.

Basic Information

Product Name	Ethyl 4-Chloro-2-Thien-2-Ylpyrimidine-5-Carboxylate
CAS No.	188937-40-8
Molecular Formula	C11H9ClN2O2S
Molecular Weight	268.72 g/mol
Synonyms	Ethyl 4-chloro-2-(thiophen-2-yl)pyrimidine-5-carboxylate; 4-Chloro-2-(2-thienyl)-5-pyrimidinecarboxylic acid ethyl ester; 5-Pyrimidinecarboxylic acid, 4-chloro-2-(2-thienyl)-, ethyl ester; 188937-40-8; Ethyl 4-chloro-2-(2-thienyl)pyrimidine-5-carboxylate; 2-(Thiophen-2-yl)-4-chloropyrimidine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-Thien-2-Ylpyrimidine-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.