Description

6-Fluorochroman-8-Ol is a fluorinated chroman derivative, a versatile and high-value organic intermediate in advanced chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms or chroman scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in developing new generation pesticides and herbicides where the fluorochroman structure can enhance biological activity and stability.
• Material Science: Serves as a precursor for functional organic materials, including liquid crystals and organic light-emitting diodes (OLEDs).
• Chemical Synthesis: A versatile synthon for introducing fluorine and phenolic hydroxyl groups into complex organic molecules in medicinal and process chemistry.
• Academic & R&D: Used in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Fluorine Chemistry: A valuable substrate for studying fluorination reactions and the effects of fluorine substitution on chroman systems.

Basic Information

Product Name	6-Fluorochroman-8-Ol
CAS No.	188826-25-7
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	8-Hydroxy-6-fluorochroman; 6-Fluoro-8-hydroxychroman; 6-Fluorochroman-8-ol; 6-Fluoro-3,4-dihydro-2H-1-benzopyran-8-ol; 2,3-Dihydro-6-fluoro-8-hydroxy-2H-1-benzopyran; 6-Fluoro-8-hydroxy-3,4-dihydro-2H-chromene
EINECS	Contact for details

Quality Control

Our 6-Fluorochroman-8-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from research quantities to commercial scale, ensuring reliable supply for critical R&D and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.