Description

Ethyl 2-Chloro-4-Methylpyrimidine-5-Carboxylate is a high-purity pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular construction. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and antiviral applications.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging its pyrimidine core for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: An essential building block in multi-step synthetic routes for final API production under GMP conditions.
• Material Science Precursor: Potential intermediate for the synthesis of organic ligands and functional materials.

Basic Information

Product Name	Ethyl 2-Chloro-4-Methylpyrimidine-5-Carboxylate
CAS No.	188781-08-0
Molecular Formula	C9H11ClN2O2
Molecular Weight	214.65 g/mol
Synonyms	2-Chloro-4-methylpyrimidine-5-carboxylic acid ethyl ester; Ethyl 2-chloro-4-methyl-5-pyrimidinecarboxylate; 5-Carbethoxy-2-chloro-4-methylpyrimidine; 2-Chloro-4-methyl-5-ethoxycarbonylpyrimidine; 188781-08-0; Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-chloro-4-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-4-Methylpyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.