Description

Ethyl 2-Hydroxy-4-Phenylpyrimidine-5-Carboxylate is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel compounds with specific biological or functional properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting kinase inhibition or other therapeutic pathways.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators that require a pyrimidine core structure.
• Material Science Research: Serves as a precursor for creating specialized organic ligands, coordination polymers, or organic electronic materials.
• Chemical Research & Development: Employed as a versatile building block for constructing complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	Ethyl 2-Hydroxy-4-Phenylpyrimidine-5-Carboxylate
CAS No.	188781-06-8
Molecular Formula	C₁₃H₁₂N₂O₃
Molecular Weight	244.25 g/mol
Synonyms	Ethyl 2-hydroxy-4-phenyl-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 2-hydroxy-4-phenyl-, ethyl ester; 2-Hydroxy-4-phenylpyrimidine-5-carboxylic acid ethyl ester; 4-Phenyl-2-hydroxypyrimidine-5-carboxylic acid ethyl ester; Ethyl 4-phenyl-2-oxo-1,2-dihydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Hydroxy-4-Phenylpyrimidine-5-Carboxylate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.