Description

4-(4-Benzyl-1-Piperazinyl)-6-Chloropyrimidine is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds in custom synthesis and process development.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and early-stage development of potential APIs requiring the piperazinyl-pyrimidine pharmacophore.

Basic Information

Product Name	4-(4-Benzyl-1-Piperazinyl)-6-Chloropyrimidine
CAS No.	188527-14-2
Molecular Formula	C15H17ClN4
Molecular Weight	288.78 g/mol
Synonyms	6-Chloro-4-(4-benzylpiperazin-1-yl)pyrimidine; 4-(4-Benzylpiperazin-1-yl)-6-chloropyrimidine; 6-Chloro-4-(4-benzyl-1-piperazinyl)pyrimidine; 1-(6-Chloropyrimidin-4-yl)-4-benzylpiperazine; 4-(4-Benzylpiperazino)-6-chloropyrimidine; 188527-14-2; 4-(4-Benzyl-1-piperazinyl)-6-chloro-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(4-Benzyl-1-Piperazinyl)-6-Chloropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.