Description

D-Isoleucine, 2-Methyl- (9Ci) CAS NO 188359-25-3 is a specialized, non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis and pharmaceutical research. Its unique stereochemistry and methyl substitution pattern make it a valuable chiral building block for the development of novel bioactive compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to incorporate complex, tailor-made amino acid motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in peptide mimetics and metabolic modulators.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and plant growth regulators that require specific stereochemical configurations for optimal activity.
• Biochemical Research: Serves as a standard or precursor in metabolic pathway studies and enzyme inhibition assays due to its structural similarity to natural isoleucine.
• Fine Chemical Production: Employed as a building block for synthesizing complex organic molecules, flavors, and fragrances where precise stereocontrol is critical.
• Peptidomimetic Design: Integral for developing peptide analogs with enhanced stability, bioavailability, and target specificity in drug discovery programs.

Basic Information

Product Name	D-Isoleucine, 2-Methyl- (9Ci)
CAS No.	188359-25-3
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(2R,3R)-2-Amino-3-methylpentanoic acid; D-allo-Isoleucine; (2R,3R)-2-Amino-3-methylvaleric acid; D-2-Methylisoleucine; (R,R)-2-Amino-3-methylpentanoic acid; D-three-Isoleucine; Non-proteinogenic D-amino acid
EINECS	Contact for details

Quality Control

Our D-Isoleucine, 2-Methyl- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, chiral analysis, and NMR spectroscopy. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.