Description

L-Alloisoleucine,2-Methyl-(9Ci) is a specialized, non-proteinogenic amino acid derivative of significant interest in advanced chemical synthesis and research. This high-purity compound serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals, bioactive peptides, and complex organic molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on stereoselective synthesis and metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in metabolic and neurological research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate non-standard amino acid residues, modifying peptide stability, activity, and conformation.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies, enzyme substrate specificity investigations, and as a probe in biochemical assays.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereocontrolled organic synthesis to create enantiomerically pure compounds.
• Nutritional Science Research: Employed in studies related to amino acid metabolism, absorption, and the biological effects of branched-chain amino acid isomers.
• Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development, validation, and quality control in analytical laboratories.

Basic Information

Product Name	L-Alloisoleucine,2-Methyl-(9Ci)
CAS No.	188359-22-0
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(2S,3S)-2-Amino-3-methylpentanoic acid; L-2-Amino-3-methylpentanoic acid; L-allo-Isoleucine; (2S,3S)-2-Amino-3-methylvaleric acid; 2-Methyl-L-alloisoleucine; (S,S)-Isoleucine; Non-proteinogenic amino acid derivative; 2-Methyl-(2S,3S)-isoleucine
EINECS	Contact for details

Quality Control

Our L-Alloisoleucine,2-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.