Description

3-Bromo-2-Chloro-5-Fluoroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a multi-functional aromatic scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex, light-fast azo dyes and high-performance pigments.
• Cross-Coupling Reactions: An excellent substrate for Buchwald-Hartwig amination, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	3-Bromo-2-Chloro-5-Fluoroaniline
CAS No.	187929-81-3
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Chloro-3-bromo-5-fluoroaniline; 5-Fluoro-2-chloro-3-bromoaniline; 3-Bromo-2-chloro-5-fluorobenzenamine; Benzenamine, 3-bromo-2-chloro-5-fluoro-; 187929-81-3; 2-Chloro-3-bromo-5-fluoro-phenylamine; 5-Amino-1-bromo-2-chloro-3-fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Chloro-5-Fluoroaniline is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee reliable performance in your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.