Description

2-(2,4-Difluorophenoxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorophenoxy aniline structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity and efficacy. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals. Its role as a key building block underscores its importance in modern organic synthesis and industrial-scale production.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, leveraging the fluorine atoms for enhanced biological activity and stability.
• Material Science Research: Acts as a monomer or precursor in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating complex molecular architectures for various applications.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for catalytic systems used in asymmetric synthesis and other fine chemical processes.

Basic Information

Product Name	2-(2,4-Difluorophenoxy)Aniline
CAS No.	187845-72-3
Molecular Formula	C12H9F2NO
Molecular Weight	221.20 g/mol
Synonyms	2-(2,4-Difluorophenoxy)benzenamine; 2-Amino-2',4'-difluorodiphenyl ether; Benzenamine, 2-(2,4-difluorophenoxy)-; 2-(2,4-Difluorophenoxy)phenylamine; 2,4-Difluorophenyl 2-aminophenyl ether; 1-Amino-2-(2,4-difluorophenoxy)benzene; 2-(2,4-Difluorophenoxy)aniline (primary name); 2-Aminophenyl 2,4-difluorophenyl ether
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenoxy)Aniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from advanced analytical techniques such as HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and impurity profiles. We are committed to meeting the stringent specifications required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.