Description

(Tyr0)-Urocortin (Rat) CAS NO 187111-93-9 is a synthetic peptide analog of the neuropeptide urocortin, specifically designed for research applications. This compound is a critical tool for investigating the corticotropin-releasing factor (CRF) receptor system and its role in stress response, anxiety, and energy homeostasis. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in neuroscience, endocrinology, and drug discovery programs.

Application

• Neuroscience Research: Used as a selective ligand to study the binding and signaling pathways of CRF receptors in the central nervous system.
• Endocrinology Studies: Employed in research on the hypothalamic-pituitary-adrenal (HPA) axis and stress hormone regulation.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool in the screening and development of novel therapeutics for anxiety, depression, and metabolic disorders.
• In Vitro & In Vivo Assays: Applied in cell-based assays and animal model studies to elucidate the physiological and behavioral effects of CRF system modulation.
• Biochemical Characterization: Utilized for the biochemical characterization of receptor subtypes and the study of peptide-receptor interactions.

Basic Information

Product Name	(Tyr0)-Urocortin (Rat)
CAS No.	187111-93-9
Molecular Formula	C206H342N62O63S
Molecular Weight	4568.3 g/mol
Synonyms	Urocortin (rat), Tyr(0)-Urocortin; [Tyr0]Urocortin; Urocortin I (rat); Rat Urocortin I; CRF-related peptide; Sauvagine-related peptide; hUCN; Ucn
EINECS	Contact for details

Quality Control

Our (Tyr0)-Urocortin (Rat) is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the product desiccated. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.