Description

Ac-Dl-6-Methyltryptophan is a modified tryptophan derivative where the amino group is acetylated and the indole ring is methylated at the 6-position. This specific structural modification makes it a valuable non-natural amino acid analog and a critical building block in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in creating novel therapeutic agents, enzyme inhibitors, and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly those targeting neurological pathways.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis to incorporate modified tryptophan residues.
• Biochemical Research: Acts as a substrate analog or inhibitor in enzymatic studies, especially for tryptophan-metabolizing enzymes like tryptophan hydroxylase or dioxygenases.
• Metabolite Standard: Employed as a reference standard in analytical chemistry for the quantification of tryptophan derivatives in complex biological matrices using HPLC or LC-MS.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study protein-protein interactions and cellular signaling processes.
• Agrochemical Research: Investigated as a potential precursor in the development of novel plant growth regulators or bioactive compounds.

Basic Information

Item	Detail
Product Name	Ac-Dl-6-Methyltryptophan
CAS No.	187028-77-9
Molecular Formula	C₁₄H₁₆N₂O₃
Molecular Weight	260.29 g/mol
Synonyms	N-Acetyl-6-methyl-DL-tryptophan; Ac-6-Me-Trp-OH; 2-Acetamido-3-(6-methyl-1H-indol-3-yl)propanoic acid; N-Acetyl-6-methyltryptophan; 6-Methyl-N-acetyltryptophan; DL-6-Methyl-N-acetyltryptophan; Acetyl-6-methyl-DL-tryptophan
EINECS	Contact for details

Quality Control

Our Ac-Dl-6-Methyltryptophan is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity, well-characterized reference materials and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.