Description

4-Amino-1-tert-Butyl-3-(3-Benzyl)Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, which serves as a critical advanced pharmaceutical intermediate. This compound is valued for its role as a versatile synthetic building block in medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the discovery and synthesis of novel drug candidates, particularly in oncology and kinase inhibitor research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for cancer therapy research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic assays to study specific biological pathways.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	4-Amino-1-tert-Butyl-3-(3-Benzyl)Pyrazolo[3,4-D]Pyrimidine
CAS No.	186895-85-2
Molecular Formula	C₁₇H₂₁N₅
Molecular Weight	295.38 g/mol
Synonyms	4-Amino-1-(tert-butyl)-3-(phenylmethyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-(tert-Butyl)-3-benzyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 3-Benzyl-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 186895-85-2; tert-Butyl 3-benzyl-4-aminopyrazolo[3,4-d]pyrimidine-1-carboxylate (related precursor); Pyrazolo[3,4-d]pyrimidine derivative
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-1-tert-Butyl-3-(3-Benzyl)Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.