Description

Pegmusirudin CAS NO 186638-10-8 is a synthetic, direct thrombin inhibitor peptide. This compound is of significant interest in pharmaceutical research and development due to its potent and specific anticoagulant activity. It is primarily utilized by researchers and manufacturers in the biopharmaceutical sector for the development of novel antithrombotic therapies and as a critical reference standard in analytical laboratories.

Application

• Pharmaceutical R&D: Serves as a key active pharmaceutical ingredient (API) or intermediate in the development of next-generation anticoagulant drugs.
• Biochemical Research: Used as a specific thrombin inhibitor in enzymatic studies and coagulation pathway investigations.
• Reference Standard: Acts as a high-purity certified reference material (CRM) for quality control and analytical method validation in pharmaceutical analysis.
• Preclinical Studies: Employed in animal models to study the efficacy and pharmacokinetics of thrombin inhibition.
• Diagnostic Reagent Development: Utilized in the formulation of specialized diagnostic kits for monitoring blood coagulation parameters.

Basic Information

Product Name	Pegmusirudin
CAS No.	186638-10-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pegmusirudin; PEG-Musirudin; PEGylated Musirudin; Polyethylene glycol-Musirudin conjugate; Recombinant Hirudin PEG conjugate; Thrombin Inhibitor PEG Conjugate; (Additional IUPAC/systematic names available on request)
EINECS	Contact for details

Quality Control

Our Pegmusirudin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, peptide mapping, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, potency, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (Related Substances, HPLC)	Total impurities ≤ 5.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Contact for details
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.