Description

5-Bromo-2,3-Difluorophenol is a halogenated fluorophenol derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromine and fluorine substituents on the phenolic ring, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors, particularly for developing active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic materials, contributing to improved charge transport and thermal stability.
• Polymer Chemistry: Employed in the creation of specialty polymers and epoxy resins, where it can impart flame retardancy and modify polymer chain properties.
• Organic Synthesis & Research: A valuable reagent for Suzuki-Miyaura and other cross-coupling reactions, facilitating the construction of complex biaryl structures in academic and industrial R&D.
• Dye & Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	5-Bromo-2,3-Difluorophenol
CAS No.	186590-26-1
Molecular Formula	C6H3BrF2O
Molecular Weight	208.99 g/mol
Synonyms	2,3-Difluoro-5-bromophenol; 5-Bromo-2,3-difluorophenol; Phenol, 5-bromo-2,3-difluoro-; 186590-26-1; 5-Bromo-2,3-difluoro-1-hydroxybenzene; 2,3-Difluoro-5-hydroxybromobenzene; 5-Br-2,3-F2-PhOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Difluorophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.