Description

Phenol, 5-Chloro-2,3-Difluoro- is a halogenated phenol derivative that serves as a versatile and high-value synthetic intermediate. This compound is crucial for introducing specific halogenated aromatic motifs into target molecules, enabling precise control over electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro and chloro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to modify electronic properties.
• Polymer & Resin Modification: Acts as a monomer or modifier in the production of specialty polymers, including high-performance engineering plastics and flame-retardant materials.
• Organic Synthesis & Catalysis: Employed as a ligand or precursor in cross-coupling reactions and other catalytic processes to construct complex aromatic systems.

Basic Information

Product Name	Phenol, 5-Chloro-2,3-Difluoro-
CAS No.	186590-21-6
Molecular Formula	C6H3ClF2O
Molecular Weight	164.54 g/mol
Synonyms	5-Chloro-2,3-difluorophenol; 2,3-Difluoro-5-chlorophenol; 5-Chloro-2,3-difluoro-1-hydroxybenzene; 1-Chloro-3,4-difluoro-5-hydroxybenzene; Phenol, 5-chloro-2,3-difluoro- (9CI); 186590-21-6; 5-Chloro-2,3-difluoro phenol
EINECS	Contact for details

Quality Control

Our Phenol, 5-Chloro-2,3-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.