Description

4-(1-Methyl-1H-Imidazol-2-Yl)Benzenesulphonyl Chloride is a high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactivity as an electrophile, enabling the efficient introduction of the sulfonamide functional group into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, especially those targeting enzyme inhibition via sulfonamide groups.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for synthesizing specialized polymers and functional materials with specific surface properties.
• Chemical Biology Probes: Employed in the development of activity-based probes for studying enzyme function and protein labeling.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs producing bespoke compounds for client R&D pipelines.

Basic Information

Product Name	4-(1-Methyl-1H-Imidazol-2-Yl)Benzenesulphonyl Chloride
CAS No.	186551-65-5
Molecular Formula	C10H9ClN2O2S
Molecular Weight	256.71 g/mol
Synonyms	4-(1-Methylimidazol-2-yl)benzenesulfonyl chloride; 2-(4-Chlorosulfonylphenyl)-1-methylimidazole; 1-Methyl-2-(4-sulfonylchlorophenyl)imidazole; 4-(1-Methyl-1H-imidazol-2-yl)benzene-1-sulfonyl chloride; 186551-65-5; 4-(N-Methylimidazol-2-yl)phenylsulfonyl chloride; 4-(2-Methylimidazolyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-(1-Methyl-1H-Imidazol-2-Yl)Benzenesulphonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.