Description

5-Chloro-6-Methoxynaphthalene-2-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group. This compound is critical for the synthesis of complex molecules, enabling the introduction of the sulfonamide moiety which is a key pharmacophore in modern drug discovery. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides that utilize sulfonamide chemistry.
• Dye and Pigment Manufacturing: Serves as a precursor for creating specialized naphthalene-based dyes and colorants.
• Material Science Research: Employed in the development of advanced polymers and functional materials requiring specific sulfonated aromatic units.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research due to its reactive sulfonyl chloride group.

Basic Information

Product Name	5-Chloro-6-Methoxynaphthalene-2-Sulfonyl Chloride
CAS No.	186550-37-8
Molecular Formula	C11H8Cl2O3S
Molecular Weight	291.15 g/mol
Synonyms	5-Chloro-6-methoxy-2-naphthalenesulfonyl chloride; 2-Naphthalenesulfonyl chloride, 5-chloro-6-methoxy-; 5-Chloro-6-methoxynaphthalene-2-sulphonyl chloride; 186550-37-8; 5-Chloro-6-methoxy-naphthalene-2-sulfonyl chloride; 5-Chloro-6-methoxynaphthalene-2-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Methoxynaphthalene-2-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards expected by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.