Description

7-Allyl-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially protein kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its pyrrolopyrimidine scaffold, which is common in many kinase-targeting agents.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Can be utilized in the development of chemical probes for studying specific biological pathways and enzyme functions.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for scale-up and commercial production of active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for synthetic organic chemistry research and the exploration of new heterocyclic reactions.

Basic Information

Product Name	7-Allyl-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	186519-91-5
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	4-Chloro-7-allyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 7-allyl-4-chloro-; 7-Allyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-allyl-7H-pyrrolo[2,3-d]pyrimidine; 186519-91-5; 7-Allyl-4-chloropyrrolo[2,3-d]pyrimidine; Allyl 4-chloropyrrolopyrimidine
EINECS	Contact for details

Quality Control

Our 7-Allyl-4-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.