Description

4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine is a high-value, heterocyclic building block and key synthetic intermediate. This compound matters for its crucial role in the development of novel pharmaceutical agents, particularly kinase inhibitors targeting various therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors for oncology, immunology, and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-up: Used in the development and optimization of synthetic routes for the commercial production of target drug candidates.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme function and for target validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied for the custom synthesis of more complex molecules and derivatives under cGMP or non-GMP conditions as required.

Basic Information

Item	Details
Product Name	4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS No.	186519-89-1
Molecular Formula	C12H8ClN3O2S
Molecular Weight	293.73 g/mol
Synonyms	4-Chloro-7-(benzenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(phenylsulfonyl)-; 186519-89-1; 4-Chloro-7-(phenylsulfonyl)pyrrolo[2,3-d]pyrimidine; 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(phenylsulfonyl)-7H-
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.