Description

Fmoc-Leu-Phe-Ala-Oh is a protected tripeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of custom peptide chains in automated synthesizers.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a component for creating peptide-protein or peptide-small molecule conjugates.
• Biochemical Probe Development: Incorporated into peptides used to study enzyme activity, protein-protein interactions, and cellular pathways.
• Combinatorial Chemistry Libraries: A building block for generating diverse peptide libraries for high-throughput screening.
• Academic & Institutional Research: Fundamental reagent for studies in organic chemistry, medicinal chemistry, and biochemistry laboratories.

Basic Information

Product Name	Fmoc-Leu-Phe-Ala-Oh
CAS No.	186020-93-9
Molecular Formula	C35H39N3O6
Molecular Weight	597.71 g/mol
Synonyms	Fmoc-L-F-A-OH; Fmoc-Leu-Phe-Ala; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucyl-L-phenylalanyl-L-alanine; Fmoc-Leu-Phe-Ala-OH; Fmoc-L-Leu-L-Phe-L-Ala-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methyl-N-((S)-1-(((S)-1-carboxyethyl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide; Fmoc-Leu-Phe-Ala; Fmoc-L-Leucyl-L-phenylalanyl-L-alanine
EINECS	Contact for details

Quality Control

Our Fmoc-Leu-Phe-Ala-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements, including cGMP for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.