Description

8-Fluoro-1,2-Dihydro-Naphthalene CAS NO 185918-24-5 is a fluorinated dihydronaphthalene derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a fluorine atom on an aromatic system fused to a partially saturated ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine substituent to improve efficacy and environmental profile.
• Material Science Research: Acts as a monomer or building block for developing specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic core.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological processes and protein interactions.
• Catalyst & Ligand Development: Utilized as a scaffold for creating novel chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in fluorination and cyclization reactions.

Basic Information

Product Name	8-Fluoro-1,2-Dihydro-Naphthalene
CAS No.	185918-24-5
Molecular Formula	C₁₀H₉F
Molecular Weight	148.18 g/mol
Synonyms	8-Fluoro-1,2-dihydronaphthalene; 1,2-Dihydro-8-fluoronaphthalene; 8-Fluoro-1,2,3,4-tetrahydronaphthalene (common misnomer, note correct saturation); 8-F-DHN; 8-Fluoronaphthalene, 1,2-dihydro-; 185918-24-5; 8-Fluoro-1,2-dihydronaphthalene
EINECS	Contact for details

Quality Control

Our 8-Fluoro-1,2-Dihydro-Naphthalene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.