Description

1-Propanone, 2-Chloro-1-(5-Fluoro-2,4-Dihydroxyphenyl)- (9Ci) is a specialized halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, or organic electronic materials due to its unique aromatic and halogenated structure.
• Chemical Synthesis: Acts as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl systems.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies in organic chemistry and medicinal chemistry programs.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	1-Propanone, 2-Chloro-1-(5-Fluoro-2,4-Dihydroxyphenyl)- (9Ci)
CAS No.	185843-78-1
Molecular Formula	C9H6ClFO3
Molecular Weight	216.59 g/mol
Synonyms	2-Chloro-1-(5-fluoro-2,4-dihydroxyphenyl)ethanone; 2-Chloro-1-(5-fluoro-2,4-dihydroxyphenyl)propan-1-one; 2-Chloro-1-(5-fluoro-2,4-dihydroxyphenyl)acetone; 5-Fluoro-2,4-dihydroxy-α-chloroacetophenone; 1-(5-Fluoro-2,4-dihydroxyphenyl)-2-chloropropan-1-one; α-Chloro-5-fluoro-2,4-dihydroxyacetophenone; 185843-78-1; 2-Chloro-1-(5-fluoro-2,4-dihydroxyphenyl)propanone
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 2-Chloro-1-(5-Fluoro-2,4-Dihydroxyphenyl)- (9Ci) adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.