Description

n-α-Boc-Nepsilon-Dansyl-L-Lysine is a specialized, dual-protected derivative of the amino acid L-lysine, featuring Boc (tert-butyloxycarbonyl) and Dansyl (5-dimethylaminonaphthalene-1-sulfonyl) protecting groups. This compound is essential for advanced peptide synthesis and biochemical research, where selective protection and fluorescent labeling are required. It is primarily utilized by pharmaceutical R&D teams, peptide chemistry laboratories, and diagnostic developers working on fluorescence-based assays and probes.

Application

• Peptide Synthesis Intermediate: Serves as a critical building block in solid-phase and solution-phase peptide synthesis, allowing for the orthogonal deprotection of amino groups.
• Fluorescent Probe Development: The dansyl fluorophore enables its use in creating fluorescently tagged peptides for studying protein-protein interactions, receptor binding, and cellular localization.
• Biochemical Research Reagent: Used in enzyme studies, substrate mapping, and as a tracer molecule in various bioanalytical techniques.
• Pharmaceutical Intermediate: Employed in the research and development stages of novel therapeutic peptides and peptide-based drugs.
• Diagnostic Assay Component: Can be incorporated into the design of fluorescent immunoassays and other diagnostic tools.
• Standards and Reference Material: Provides a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	n-α-Boc-Nepsilon-Dansyl-L-Lysine
CAS No.	185504-01-2
Molecular Formula	C24H37N3O6S
Molecular Weight	495.63 g/mol
Synonyms	Boc-Lys(Dns)-OH; Nα-Boc-Nε-dansyl-L-lysine; (S)-2-((tert-Butoxycarbonyl)amino)-6-(5-(dimethylamino)naphthalene-1-sulfonamido)hexanoic acid; Boc-Lys(Dnp)-OH (common alternate); N-Boc-N'-dansyl-L-lysine; L-Lysine, N2-[(1,1-dimethylethoxy)carbonyl]-N6-[5-(dimethylamino)-1-naphthalenesulfonyl]-; Dansyl-L-lysine N-Boc derivative; Fluorescent lysine derivative
EINECS	Contact for details

Quality Control

Our n-α-Boc-Nepsilon-Dansyl-L-Lysine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure enantiomeric purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.