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Hexanoic Acid, 6-[(Carboxymethyl)[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 1-(1,1-Dimethylethyl) Ester CAS NO 185426-32-8


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CAS No.:185426-32-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Hexanoic Acid, 6-[(Carboxymethyl)[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated, protected amino acid derivative designed for advanced synthetic applications. This compound is a critical building block in the synthesis of complex peptides and other bioactive molecules, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

  • Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid derivative for the controlled assembly of peptide chains.
  • Pharmaceutical Intermediates: Used in the research and development of active pharmaceutical ingredients (APIs) and prodrugs.
  • Bioconjugation: Acts as a linker or spacer molecule for attaching functional groups to proteins, antibodies, or other biomolecules.
  • Chemical Biology Research: Employed in the study of protein-protein interactions and enzyme mechanisms.
  • Protecting Group Chemistry: The tert-butyl ester and Fmoc-protected amine provide orthogonal protection strategies in multi-step organic syntheses.
  • Material Science: Potential use in creating functionalized polymers and advanced materials with specific surface properties.

Basic Information

Product Name Hexanoic Acid, 6-[(Carboxymethyl)[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 1-(1,1-Dimethylethyl) Ester
CAS No. 185426-32-8
Molecular Formula C27H31NO6
Molecular Weight 465.54 g/mol
Synonyms Fmoc-Lys(Boc)-OH; Nε-Boc-Nα-Fmoc-L-lysine; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine; Fmoc-Lys(Boc)-OH; Boc-Lys(Fmoc)-OH; (2S)-6-({[(1,1-Dimethylethoxy)carbonyl]amino})-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid; Nα-Fmoc-Nε-Boc-L-lysine; Fmoc-Lys(Boc)
EINECS Contact for details

Quality Control

Our Hexanoic Acid, 6-[(Carboxymethyl)[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and chiral integrity suitable for demanding research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Assay (HPLC) ≥98.0%
Optical Rotation Contact for details
Water Content (KF) ≤0.5%
Heavy Metals ≤10 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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