Description

n-(1,4-Dihydro-1,4-Dioxo-2-Naphthalenyl)-L-Tryptophan is a specialized, high-purity synthetic organic compound that serves as a critical building block in advanced pharmaceutical and biochemical research. Its unique molecular structure, combining a tryptophan moiety with a naphthalenedione group, makes it a valuable intermediate for developing novel therapeutic agents and biochemical probes. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways or receptor sites.
• Biochemical Research: Used as a specialized reagent or probe in studying protein-ligand interactions, enzyme mechanisms, and cellular signaling pathways.
• Peptide & Conjugate Synthesis: Serves as a modified amino acid building block for creating peptide-based compounds or antibody-drug conjugates (ADCs) with enhanced properties.
• Fluorescent Probe Development: The naphthalenedione moiety can be utilized in the design of fluorescent markers or sensors for analytical and diagnostic applications.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for investigative chemistry and medicinal chemistry projects.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for material science or specialty chemical applications.

Basic Information

Product Name	n-(1,4-Dihydro-1,4-Dioxo-2-Naphthalenyl)-L-Tryptophan
CAS No.	185351-19-3
Molecular Formula	C₂₃H₁₈N₂O₄
Molecular Weight	386.40 g/mol
Synonyms	L-Tryptophan, N-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-; 2-[(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)amino]-3-(1H-indol-3-yl)propanoic acid; N-(1,4-Dioxo-1,4-dihydronaphthalen-2-yl)-L-tryptophan; 185351-19-3; Tryptophan derivative with 1,4-naphthoquinone; Naphthalenedione-L-tryptophan conjugate
EINECS	Contact for details

Quality Control

Every batch of n-(1,4-Dihydro-1,4-Dioxo-2-Naphthalenyl)-L-Tryptophan is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products meet high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, chiral purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.