Description

3-Bromo-5-Fluoro-4-Hydroxybenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and aldehyde functional groups on a phenolic ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and chemical manufacturers engaged in developing pharmaceuticals and agrochemicals, where it serves as a key precursor for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials, including ligands for metal complexes and core structures for liquid crystals and light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific characteristics such as flame retardancy, altered refractive index, or enhanced thermal stability.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions, catalytic processes, and as a standard in analytical method development.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	3-Bromo-5-Fluoro-4-Hydroxybenzaldehyde
CAS No.	185345-46-4
Molecular Formula	C7H4BrFO2
Molecular Weight	219.01 g/mol
Synonyms	4-Hydroxy-3-bromo-5-fluorobenzaldehyde; 3-Bromo-5-fluoro-4-hydroxybenzaldehyde; 5-Fluoro-3-bromo-4-hydroxybenzaldehyde; Benzaldehyde, 3-bromo-5-fluoro-4-hydroxy-; 3-Bromo-5-fluorosalicylaldehyde (common name); 185345-46-4 (CAS); 3-Br-5-F-4-OH-BzH (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-4-Hydroxybenzaldehyde is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality protocols are designed to support compliance in cGMP and ISO 9001 environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.