Description

3-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of fluorine atoms and a reactive benzyl alcohol group, which facilitates the introduction of specific physicochemical properties into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and oncology research, where fluorine substitution is used to modulate metabolism and bioavailability.
• Agrochemical Synthesis: Serves as a precursor for advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to enhance biological activity and environmental stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated liquid crystal compounds for high-performance displays (LCDs), where it contributes to improved dielectric anisotropy and thermal stability.
• Polymer & Material Science: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, lower surface energy, and improved optical properties.
• Organic Synthesis Building Block: The benzyl alcohol group can be readily functionalized (e.g., esterification, etherification, oxidation) to create a diverse array of more complex fluorinated derivatives for various research applications.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	184970-29-4
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	(3-Fluoro-5-(trifluoromethyl)phenyl)methanol; α,α,α-Trifluoro-3-fluoro-5-tolylcarbinol; 3-Fluoro-5-trifluoromethylbenzyl Alcohol; 1-(3-Fluoro-5-(trifluoromethyl)phenyl)methanol; 3-Fluoro-α,α,α-trifluoro-m-tolylmethanol; 3-Fluoro-5-(trifluoromethyl)benzenemethanol; 5-(Trifluoromethyl)-3-fluorobenzyl Alcohol
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized and released against comprehensive specifications, which typically include identity confirmation (IR, NMR), purity assay (HPLC, GC), and control of key impurities. A Certificate of Analysis (COA) detailing the results for each batch is provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.