Description

4-Chloro-5-Fluoro-2-Nitrobenzaldehyde is a versatile and high-purity aromatic aldehyde building block, essential for advanced organic synthesis. Its unique halogenated nitrobenzene structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro-nitro substitution pattern contributes to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Liquid Crystal & Dye Intermediates: Employed in the production of specialty chemicals for electronic displays and high-performance pigments.
• Cross-Coupling Reactions: The aldehyde and halogen groups make it a valuable substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Academic & Contract Research: Utilized in research laboratories for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	4-Chloro-5-Fluoro-2-Nitrobenzaldehyde
CAS No.	184843-93-4
Molecular Formula	C7H3ClFNO3
Molecular Weight	203.56 g/mol
Synonyms	2-Nitro-4-chloro-5-fluorobenzaldehyde; 4-Chloro-5-fluoro-2-nitrobenzaldehyde; 5-Fluoro-4-chloro-2-nitrobenzaldehyde; Benzaldehyde, 4-chloro-5-fluoro-2-nitro-; 184843-93-4; 4-Chloro-5-fluor-2-nitrobenzaldehyd; 4-Chloro-5-fluoro-2-nitro-benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-Nitrobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.